...HER2阳性转移性乳腺癌；帕妥珠单抗；拉帕替尼；临床试验；安全性；不良事件；新药审评；上市后承诺及要求 [gap=977]Key words： HER2 positive metastatic breast cancer; pertuzumab; lapatinib; clinical trials; safety; adverse events (AE); NDA/BLA r..

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